Scanning: FMR’s Sleep Deprived v. Post Partum Depression

Postpartum Depression

Articles showing images of brains’ of women with Postpartum Depression:

Image reveals individuals inability to response to negative input.

Image reveals individual's inability to response to negative input.

CMS Spectrums, the International Journal of Psychiatric Medicine, has a detailed research paper online, showing several brainscans.

Brain Acitivty Visibly Altered During Sleep Deprivation

FMRI images of sleep deprived brain of Pospartum patients

It is possible that when the prefrontal and temporal regions were affected by sleepiness, the brain shifted the verbal processing to another system in the parietal lobes that could compensate for the loss of function. This suggests that parietal lobes might play a special role in the brain’s compensation for sleepiness,” said Gregory G. Brown, Ph.D., associate professor of psychiatry at UCSD and a member of the team.

“However, the parietal lobes are the system primarily associated with arithmetic performance when subjects are well rested, so when it becomes less responsive with sleeplessness, there is not a brain system available to come online to compensate for the negative effects of sleep deprivation,” he said.

Circadian Rhythms & Wake Therapy: Using Bright Light in AM to prevent CR from slowing down:

  • RITEWAVE Therapy 15-30 minutes in the morning can help produce serotonin and reset your body clock. Resetting your body clock will also allow you to fall asleep easier and sleep better throughout the night. BRITEWAVE light is specially designed to produce the active hormone, serotonin and suppress melatonin. Melatonin is often called the ‘hibernation hormone’ and is thought to restrict other hormones that promote a healthy menstrual cycle. Your body produces higher levels of melatonin during the winter, and when you don’t get enough bright light. PMDD is also worse in the winter.
  • Wake Therapy has been used successfully with women for stronger symptoms of postpartum depression. With the guidance of a physician, try waking up early, around 2:00 am (for one morning only) before your period starts, and use BRITEWAVE light each morning through the first week of your next cycle.
  • Increase Serotonin Levels . Low levels of serotonin are related to depression, mood, irritability, low concentration and pain. Women are more vulnerable to serotonin deficiency than men. In addition to BRITEWAVE therapy, Apollo’s Harmony™ works with BRITEWAVE to balance your serotonin levels

Read article for more;Circadian Rhythms:

Sleep deprived brain

Sleep Deprived Brain

Sleep Deprived Brain

Sleep-deprived brains alternate between normal activity and ‘power failure’

excerpt: Previous research showed that attentional lapses normally induce activity in frontal and parietal regions of the brain, “command centers” that may compensate for lost focus by increasing attention. However, during attentional lapses, Chee and colleagues found reduced activity in these brain command centers in sleep-deprived compared to well-rested volunteers. This finding suggests that sleep deprivation reduces the brain’s ability to compensate for lost focus.

Sleep-deprived people also showed reduced activity in brain regions involved in visual processing during attentional lapses. Because the brain becomes less responsive to sensory stimuli during sleep, reduced activity in these regions suggests that, during attentional lapses, the sleep-deprived brain enters a sleep-like state.

“To my knowledge, this is one of the first studies to look carefully at brain imaging during lapses of consciousness after sleep deprivation, the equivalent of ‘blanking out,’” said Emmanuel Mignot, MD, PhD, at Stanford University, who was not involved in the study. Although attentional lapses result in the same behaviors, “lapses due to sleep deprivation are clearly different neurobiologically than lapses in well-rested people,” Mignot said.

Brain severely sleep deprived

Right Image: Brain severely sleep deprived

Sleep deprivation disconnects the emotional brain

sleep-deprived participants showed larger amygdala responses, and their amygdalas showed weaker functional connectivity with medial prefrontal cortex. This finding does not prove that the greater amygdala response in the sleep-deprived group was caused by the weakened connectivity with medial prefrontal cortex, but it is certainly consistent with that notion. Yoo et al suggest that sleep acts as a kind of reset of brain reactivity, to ensure that emotional challenges can be met appropriately. But why is such a reset necessary in the first place? Why is the regulatory influence of medial prefrontal cortex weakened by sleep deprivation?

~ by boatsie on August 2, 2008.

One Response to “Scanning: FMR’s Sleep Deprived v. Post Partum Depression”

  1. Totally fascinating stuff.

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