“There have been some who have experienced electric shock sensations when stopping Effexor and some other serotonin agents such as Cymbalta, Paxil, etc. This is very unusual, but I’ve heard patients describe it as a “brain shock” that was worsened with movement. In the literature, reports of these symptoms last up to 5 days.
The origin of these sensations is not entirely clear, but thought to be a form of paresthesia (which is the sensation of feeling tingling or creeping on the skin). Paresthesias result from our nerves being activated in a particular area when there is no apparent trigger for the activation – for example, feeling a pinprick on your skin when you haven’t been pricked by a pin.” Link
How to survive brain shivers?
Brain shivers is a non-medical term used by some internet bloggers described as an electrical sensation. Those who complain about brain shivers have recently stopped or are taking certain antidepressants called selective serotonin reuptake inhibitors (SSRIs). SSRIs affect the serotonin levels by blocking absorption by certain nerve cells, which results in more serotonin in the brain cells, increasing nerve impulses. Link
Antidepressants and other medications deplete the body and brain of glutathione. Effexor withdrawal help role of glutathione in the body has been proven to be essential in the treatment of disease.